Given the new view of the 100 trillion microbes that are tolerated by the immune system a new paradigm of immune system function is needed. The basic tenets of this new view have been updated:
Immune system development and healthy function
requires continual interaction with the mutualist
microbes, the beneficial bacteria and parasites.
- A central component of balance in the immune system is achieved by the function of a recently discovered peacekeeper faction of the immune system: Regulatory T cells and Regulatory B cells that rein in the immune response.
- These regulatory peacekeepers are produced primarily when our immune systems regularly engage with our microbiome: bacteria and parasites
- If the microbiome biodiversity declines, then immune system education is compromised, microbe encounters decline and the peacekeeper levels fall. This situation is responsible for precipitating inflammation, allergies, asthma, and autoimmune imbalances.